2016-06-05 02:26
proband翻译
先证者
音标读音
英式:['prəʊbænd]美式:['proʊbænd]
基本意思
n.（家系研究中尤指遗传疾病的家属史研究中的）渊源者，先证者，基人
形近的词
变形
例句
- The parents of a proband are obligate heterozygotes and therefore carry one mutant allele.
先证者的父母必定是杂合子，各携带一个突变等位基因。
- Results No mutation of GJB6 and GJB3 genes was found in the proband and her parents.
结果先证者及其父母GJB3、GJB6基因测序未发现突变。
- The risk to the sibs of a male proband depends upon the carrier status of the mother.
男性先证者的同胞的患病风险取决于其母亲的携带者状态。
- Methods: Family-based nonparametric genome-wide linkage analysis was performed in by either an HLHS or BAV proband.
方法：在有左室发育不全和二叶式主动脉瓣先证者的家系中进行非参数基因组连锁分析。
- Prophase Study of Gene Mutation and Mutant Compensation on Familial Hypercholesterolemia Proband
家族性高胆固醇血症患者LDL受体基因突变及突变基因补偿的前期研究
- The Study on the Impact of Onset Age of the Type 2 Diabetes Proband on the Genetic Phenotype CHEN
2型糖尿病先证者发病年龄对遗传表型影响的研究
- Methods The clinical data of 23 children suffering from spinal muscular atrophy were analyzed using Weiber proband method to find the inheritance pattern of pathogenesis.
方法对23例脊肌萎缩症患儿的临床资料进行总结，并用Weiber先证法分析其发病的遗传规律。
- The results indicatad that the proband, his mother and his daughter all were identified to be Bel phenotype;
结果表明：先证者与其母、女儿3人确定为Bel亚型；
- Carrier testing for at-risk family members may be available once the CBS mutations have been identified in the proband.
如果先证者的CBS突变被鉴定，也可能提供有风险的家族成员进行携带者检测。
- The proband of pedigree A with highexpression of fragile X chromosome ( 35/ 273) was detected to be a full mutation patient of fragile X syndrome by the molecular genetic test.
A家系先证者脆性X染色体高表达（35273），分子遗传学检查证实为脆性X综合征全突变患者；
- Methods& Studies were included in the present review if they reported the frequency of family history of stroke in relation to sex of parent or proband.
方法：研究包括目前已发表综述中所有有关脑卒中遗传与性别相关的论述，而且若有必要，我们会联系文章的作者索取未发表的数据。
- F ⅶ gene mutations were analysed in the proband and her family members by DNA direct sequencing.
用DNA直接测序法对先证者及其家庭成员F基因的全部外显子和其侧翼以及启动子进行分析，寻找基因突变；
- Methods: Pedigree investigation and pathological examination in the muscle biopsy of proband and his aunt were carried out.
方法：对该家系进行家系调查，对先证者及其姑母进行肌活检组织学观察。
- The proband is a homozygote for this deletion mutation, with milder anemia than that of typical homozygotes of β-thalassemia.
先证者为这一缺失的纯合子，具有中度贫血症状。
- Results: Bel phenotype was found in three family members including proband and his mother and daughter.
结果：在一个汉族的家系3代中发现3例Bel亚型，先证者及其母亲和女儿均为Bel亚型。
- The result of cephalometric analysis indicated no obvious inherited tendency in the proband in terms of facial osseo type and jaw bone pattern.
头影测量分析结果提示先证者在骨面型及颌骨形态等方面无明显遗传倾向。
- Methods Proband with FASD and families members were evaluated by detailed history and physical examination, 12-lead ECG, 2D Doppler echocardiography.
方法对一个家系的患者和家族成员的病史、体征、心电图、彩色多普勒超声心动图等进行调查分析。
- The most frequently cited symptoms by first-degree relatives and spouse in MDD were weight change and indecisive. BPD's family members provided more manic symptoms than those reported from proband.
忧郁症患者的一等亲、配偶与患者本身回报相似数量的忧郁症症状，但双极症患者的一等亲与配偶较患者本身提供更多的躁症症状资讯。
- Restriction enzyme analysis confirmed: the proband is the missense mutation carrier, MH susceptible person.
限制酶分析确认：临床确诊者及其母亲为该错义突变携带者，为MH易感者。
- Methods Asthmatic family was collected using the proband as the center.
方法以先证者为调查中心，收集哮喘家系，对每个家系成员进行病史调查同时作支气管反应性测定或支气管舒张试验。
- The results showed that phenotype of the proband was diagnosed as afibrinogenemia.
结果表明：先证者表型诊断为无纤维蛋白原血症；
- Methods: The clinical manifestation, EEG, Video-EEG, and MRA were observed in the proband.
方法：对先证者进行详尽的临床、脑电图（EEG）、录像脑电图（Video-EEG）、头MRA观察。
- Objective To detect gene mutation in proband from a family with piebaldism.
目的研究一斑驳病家系先证者的基因突变情况。
- Parents of proband were heterozygous carriers.
先证者父母为杂合缺失携带者。
- The proband's twin sister also suffered from diabetic mellitus over 2 years and recurrent vertigo.
另一孪生妹妹在2年前亦发现糖尿病，曾经有过头晕发作。
- Testing of relatives at risk: It is appropriate to test sibs of a proband so that appropriate dietary management can be instituted before symptoms occur.
亲属的基因测定：家族进行基因测定来确认渊源者，这样才能在症状发作的时候，提供适当的饮食控制。
- The hereditary degree of class I kinfolks of proband was 58.74% ± 5.43%.
先证者一级亲属的遗传度为（58.74±5.43）%。
- This paper reports the clinical hematological data of proband and the results of gene analysis, as well as a preliminary discussion on the characteristics and significance of its distribution.
现报告先证者的临床血液学资料和基因分析结果，并对它的分布特点和意义进行初步讨论。
- CDH1 mutational analysis and pathologic study of a Chinese familial cancer syndrome with diffuse type gastric cancer/ breast cancer proband
胃癌/乳腺癌先证者家族性癌症综合征家系CDH1突变分析及病理学特征
- In this way, it will be very difficult to diagnose without proband.
这样，在没有先证者的情况下有时很难做出诊断。
百科解释
网络意思